An cDNA fragment was isolated from Halostachys caspica by suppression subtractive hybridization and its full-length cDNA with 2 090 bp was cloned by SMART^TM RACE,which consisted of a 1 635 bp open reading frame encoding 544 amimo acids with molecular weight of 61.503 kD and an isoelectric point of 6.1,a 294 bp 5′-UTR and 161 bp 3′-UTR.The deduced amino acid sequence got together with that of GRAS family protein VvSCL13 from Vitis vinifera and had a C-terminal conserved domain,so it was named HcSCL13 gene (GenBank accession number KC68640).Real-time PCR method was performed to investigate the expression profile of HcSCL13 gene under salt stress.HcSCL13 showed up-regulated expression patterns under salt treatment.Based on our results,we concluded that HcSCL13 gene might be involved in salt response and one of important components for the salt tolerant pathway in H.caspica.